Such ordinary people
Matteo was born in Lecco (IT) and he graduated in Biomedical Engineering from the Polytechnic University of Milan in 2005.
After a few years spent as a junior fellow at the IRCCS 'Medea' (Bosisio Parini, IT), he got his Ph.D. in Complex system in Genomics from the University of Turin in 2010. During this time, Matteo joined the group of Jernej Ule at the MRC LMB (Cambridge, UK), where he focused on protein-RNA interactions.
As a postdoc, he moved to the European Institute of Oncology (IEO) and then at the King's College London (UK) in the group of Francesca Ciccarelli. There he studied tumor evolution and heterogeneity in cancer progression and drug resistance being involved in large cancer sequencing programs.
Since 2019 he leads the Cancer Genomics and Bioinformatics (CGB) unit at the Italian Institute for Genomic Medicine (IIGM) in Torino. Since 2021 Matteo has been appointed as Associate Professor of Molecular Biology at the University of Milan "La Statale" Matteo is interested in:
Serena graduated in Physics of Complex Systems at the university of Torino in 2018 presenting a work on network analysis of alternative splicing regulation to detect cancer-specific alterations. She joined the CGB lab entering the Ph.D. school of Complex Systems for Life Science in October 2018. Serena got her Ph.D. in 2021 from the University of Turin. As a post-doc, Serena is responsible for sereval projects ranging from cancer genomics to RNA biology and therapy. Her interests are:
Francesca graduated in Mathematical Engineering at the University of Padova in 2018 with a thesis in epidemiology concerning the interplay between disease and information spreading in multiplex networks, performed at the Institute for Biocomputation and Physics of Complex Systems (BIFI) in Zaragoza. As a master student, Francesca entered the Erasum program visiting the Technical University of Eindhoven (Tu/E) at the department of Mathematics and Computer science. After her graduation she worked as an IT consultant in ALTEN and since September 2019 she joined the C.G.B. lab. Francesca is now Ph.D. student in Complex Systems for Quantitative Biomedince at University of Torino. Francesca is interested in:
Sarah graduated in Physics of Complex Systems at the University of Torino in 2019 with a dissertation of the impact of gene expression modality on biological processes at a single cells. She joined the CGB lab as a master student and she is no Ph.D. student in Complex Systems for Quantitative Biomedicine at the University of Torino. Sarah is interested in:
Master student from the University of Milan, Mariachiara return to our lab after two years to continue her work on of long-read direct mRNA sequencing data generated using Oxford Nanopore Technologies. Mariachiara is interested in:
Livia contributed to the experimental validations of FOXA1-mediated regulation of alternative splicing in prostate cancer. During the mounths spent in our lab she was also responsible for the devolopment of several other projects aiming at understanding alternative splicing regulation in cancer. She is now post-doc in the Epigenetics Lab of Prof Oliviero at the University of Turin!
Marco contributed to the identified of pioneer transcription factor FOXA1 as the key controller of alternative splicing in prostate cancer. His contribution revealed that FOXA1 controls selection of splice variants that predict disease relapse and might be new drug targets to improve patient survival. He is now data scientist at industry!
Alberto importantly contributed to the improvment of RNAmotifs, which can now associate multivalent RNA motifs with cognate RNA binding proteins. He is data scientist at industry!
Lucilla analyzed DNA somatic alterations in pediatric Ewing's sarcoma.
Jessica was involved in trascriptomic analyses of breast cancer chemioresistant tumors. She is now professor at secondary high school and still free-lance bioinformatician collaborating with us!
Greta worked on the characteziation of tumor evolution within the Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas (NCT04621201) Trials, focusing on DNA somatic alterations. She decided to foster her training in Biology and she is now enrolled in postgraduate school of Medicine at the University of Parma.
Federica was the first biologist post-doc in our lab. She contributed to settle our experimental biology lab, implementing the Oxford Nanopore Technologies direct mRNA protocol and the Lexogen CORALL protocol for total mRNA sequencing. She is now professor at secondary high school!
We discuss our ideas with talented people: