The C.G.B. team

Such ordinary people

Group Leader


Matteo Cereda

M.Eng., Ph.D.

Matteo was born in Lecco (IT) and he graduated in Biomedical Engineering from the Polytechnic University of Milan in 2005. After a few years spent as a junior fellow at the IRCCS 'Medea' (Bosisio Parini, IT), he got his Ph.D. in Complex system in Genomics from the University of Turin in 2010. During this time, Matteo joined the group of Jernej Ule at the MRC LMB (Cambridge, UK), where he focused on protein-RNA interactions. As a postdoc, he moved to the European Institute of Oncology (IEO) and then at the King's College London (UK) in the group of Francesca Ciccarelli. There he studied tumor evolution and heterogeneity in cancer progression and drug resistance being involved in large cancer sequencing programs.
Since 2019 he leads the Cancer Genomics and Bioinformatics (CGB) unit at the Italian Institute for Genomic Medicine (IIGM) in Torino.

Matteo is interested in:

  • Alternative Splicing
  • Tumor evolution
  • Big Data analysis

Members


Livia Caizzi

Ph.D.

Livia received the Master degree in Biomolecular Science at the university of Turin, Italy, in 2009. Inspired by the rising advancements of next-generation sequencing and its potentiality in cancer research, she enrolled at the Ph.D. program in Complex System for Life Sciences in Turin in 2009. During this time, she studied the role of mEstrogen Receptor (ER) alpha in breast cancer development in the laboratory of Prof Michele De Bortoli. To better understand the function of ER alpha in chromatin, she started an international collaboration with Dr Luciano Di Croce at the Centre for Genomic Regulation in Barcelona, Spain, where she worked from 2011 to 2014. Livia got her Ph.D. in 2013 from the University of Turin. As a post-doc, she joined the laboratory of Dr Patrick Cramer at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany. During her post-doc she studied the mechanism underlying the coupling between the spliceosome and RNA polymerase II machinery in human cells, integrating molecular biology techniques with functional genomics. Since 2021, she is a senior scientist at C.G.B. lab.

Livia is interested in:

  • - Co-transcriptional processing
  • Functional genomics
  • Cancer genetics

Marco Del Giudice

Ph.D.

Marco graduated in Physics of Complex Systems at the University of Torino in 2014 with a theoretical work about stochastic thermodynamics in chemosensing. He then entered the Ph.D. program in Physics of the Politecnico di Torino and approached the field of computational biology. He dedicated his research to the study of gene regulatory networks, mainly working on models of microRNA-mediated gene regulation with a specific focus on the role stochastic fluctuations. During this period he also learned the basics wet-lab work and synthetic biology and developed custom pipelines for the analysis of fluorescence microscopy data. Marco got his Ph.D. in Physics in July 2018 and joined to C.G.B. lab.

Marco is interested in:

  • Machine Learning
  • Computational models
  • Tumor genetics

Serena Peirone

Ph.D. student

Serena graduated in Physics of Complex Systems at the university of Torino in 2018 presenting a work on network analysis of alternative splicing regulation to detect cancer-specific alterations. She joined the CGB lab as a Ph.D. student in Complex Systems for Life Science in October 2018.

Serena is responsible for sereval projects, from cancer genomics to SARS-Cov-2 lineage screening. Her interested are:

  • Networks and Big Data
  • Transcriptional regulation of RNA binding proteins
  • Tumor Evolution

Francesca Priante

Ph.D. student

Francesca graduated in Mathematical Engineering at the University of Padova in 2018 with a thesis in epidemiology concerning the interplay between disease and information spreading in multiplex networks, performed at the Institute for Biocomputation and Physics of Complex Systems (BIFI) in Zaragoza. As a master student, Francesca entered the Erasum program visiting the Technical University of Eindhoven (Tu/E) at the department of Mathematics and Computer science. After her graduation she worked as an IT consultant in ALTEN and since September 2019 she joined the C.G.B. lab. Francesca is now Ph.D. student in Complex Systems for Quantitative Biomedince at University of Torino.

Francesca is interested in:

  • Double Strands Breaks
  • Mathematical modelling
  • Long-read sequncing

Sarah Perrone

Ph.D. student

Sarah graduated in Physics of Complex Systems at the University of Torino in 2019 with a dissertation of the impact of gene expression modality on biological processes at a single cells. She joined the CGB lab as a master student and she is no Ph.D. student in Complex Systems for Quantitative Biomedicine at the University of Torino.

Sarah is interested in:

  • Single-cell RNA sequencing
  • Tumor evolution
  • Big Data analysis

Alberto Rissone

Research Fellow


Alumni


Fabiola Varese

Research Fellow

Fabiola extensively worked on long-read Oxford Nanopore Technologies and traditional short-read Illumina sequencing approaches. Se now moved to pharma!

Fabiola is interested in: Oxford Nanopore sequencing, RNA methylation, and Transcriptional regulation.


Jessica Giordano

Ph.D.

Jessica was involved in trascriptomic analyses of breast cancer chemioresistant tumors. She is now professor at secondary high school and still free-lance bioinformatician collaborating with us!

Jessica is interested in: RNA sequencing, Tumor evolution, and Machine Learning


Greta Romano

Ph.D.

Greta worked on the characteziation of tumor evolution within the Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas (NCT04621201) Trials, focusing on DNA somatic alterations. She decided to foster her training in Biology and she is now enrolled in postgraduate school of Medicine at the University of Parma.

Greta is interested in: Alternative Splicing, Tumor evolution, Big Data analysis.


Federica Gaudino

Ph.D.

Federica was the first biologist post-doc in our lab. She contributed to settle our experimental biology lab, implementing the Oxford Nanopore Technologies direct mRNA protocol and the Lexogen CORALL protocol for total mRNA sequencing. She is now professor at secondary high school!

Federica has interests in:Alternative Splicing, Tumor evolution, and Epitranscriptome.


Mariachiara Grieco

Intership student

Bachelor student from the University of Florence, Mariachiara visited our lab for six months and developed a pipeline for the identification of m6A methilated sites from direct mRNA sequencing data generated using Oxford Nanopore Technologies.

Mariachiara is interested in: direct mRNA sequencing, Epitranscriptome, and Oxford Nanopore Technologies.


Lorenzo Cefaloni

Intership student

C.G.B. friends  

We discuss our ideas with talented people:

Michele Caselle
Matteo Osella

Department of Theoretical Physics
Turin, IT

Prabhakar Rajan

UroSplice lab
London, UK

Uberto Pozzoli

Bioinformatics lab
Bosisio Parini, IT

Salvatore Oliviero

Dept. of Life Sciences & Systems Biology
Epigenetics Lab
Turin, IT

Davide Cacchiarelli

Armenise/Harvard Laboratory of Integrative Genomics
Naples, IT

Franca Fagioli

Paediatric Onco-Haematology, Stem Cell Transplantation and Cellular Therapy Division, City of Science and Health of Turin, Regina Margherita Children’s Hospital
Turin, IT

Francesca Ciccarelli

Cancer Systems Biology lab
London, UK

Jernej Ule

RNA Regulatory Networks lab
London, UK

Chiara Ambrogio

Armenise/Harvard Laboratory of Molecular Oncology
Turin, IT

Roded Sharan

School of Computer Science
Tel-Aviv, IL