This is the web page of our laboratory, a.k.a. Cancer Genomics and Bioinformatics.The lab has been established in 2019 @ the Italian Institute for Genomic Medicine (IIGM), located within the Candiolo Cancer Institute FPO IRCCS (IT).
Artenatively have a look here: C.G.B. @ IIGM
The lab follows three main directions
Deciphering splicing regulation in disease
Assessing tumor genetics and evolution to faster precision oncology
Designing novel algorithms to gain information from genomic Big Data
The future is unwritten
The C.G.B. highlights
Here our review on learning approaches for the analysis of large-scale RNA-sequencing datasets in cancer. We present the major solutions to disentangle tumor heterogeneity of transcriptome profiles for an effective improvement of patient management, check it out!
Together with FPO-IRCCS Candiolo units, we are actively monitoring the evolution of SARS-CoV-2 in Piedmont, Italy. The lab is mapping the virus lineages that are circulating in the region. Here some updates!
We introduced a probabilistic modelling, namely GSECA, to identify altered biological process relevant for complex phenotypes from heterogeneous high-volume RNA-seq data. Have a look at our pancancer analysis of PTEN loss and its role in modulating immune-related processes across cancer types!