The C.G.B. team

Such ordinary people

Group Leader


Matteo Cereda

M.Eng., Ph.D.

Matteo was born in Lecco (IT) and he graduated in Biomedical Engineering from the Polytechnic University of Milan in 2005. After a few years spent as a junior fellow at the IRCCS 'Medea' (Bosisio Parini, IT), he got his Ph.D. in Complex system in Genomics from the University of Turin in 2010. During this time, Matteo joined the group of Jernej Ule at the MRC LMB (Cambridge, UK), where he focused on protein-RNA interactions. As a postdoc, he moved to the European Institute of Oncology (IEO) and then at the King's College London (UK) in the group of Francesca Ciccarelli. There he studied tumor evolution and heterogeneity in cancer progression and drug resistance being involved in large cancer sequencing programs.
Since 2019 he leads the Cancer Genomics and Bioinformatics (CGB) unit at the Italian Institute for Genomic Medicine (IIGM) in Torino. Since 2021 Matteo has been appointed as Associate Professor of Molecular Biology at the University of Milan "La Statale"

Matteo is interested in:

  • Alternative Splicing
  • Tumor evolution
  • Big Data analysis

Members


Serena Peirone

Ph.D.

Serena graduated in Physics of Complex Systems at the university of Torino in 2018 presenting a work on network analysis of alternative splicing regulation to detect cancer-specific alterations. She joined the CGB lab entering the Ph.D. school of Complex Systems for Life Science in October 2018. Serena got her Ph.D. in 2021 from the University of Turin. As a post-doc, Serena is responsible for sereval projects ranging from cancer genomics to RNA biology and therapy. Her interests are:

  • RNA biology
  • Tumor Evolution
  • Networks and Big Data

Mariachiara Grieco

SEMM Ph.D. student

Mariachiara graduated in Bioinformatics for Computational Genomics at the University of Milan and Polithecnic Univesisty of Milan in 2022 with a dissertation on MYC-driven co- and post-transctional regulation in prostate cancer. During her master thesis project Mariachiara analyzed long-read direct mRNA sequencing data generated using Oxford Nanopore Technologies. Since October 2022 Mariachiara joined the Ph.D. program at the European School of Molecular Medicine (SEMM) from the University of Milan.

Mariachiara is interested in:

  • RNA biology
  • Genomic instability
  • Long-read sequencing

Tommaso Becchi

SEMM Ph.D. student

Tommaso graduated in Bioinformatics at the university of Bologna in 2021 presenting a new algorithm for the reconstruction of gene co-expression networks.He joined our lab in 2023 firstly as a research fellow and then entering the European School of Molecular Medicine (SEMM) from the University of Milan. His interests are:

  • RNA biology
  • Artificial Intelligence
  • Long-read sequencing

Vivian P. Lagkada

Ph.D. student

Her interests are:

  • RNA biology
  • KRAS biology
  • Long-read sequencing

Debora Caprella

Ph.D. student

Debora graduated in Genetics and Molecular Biology at the Sapienza University with a dissertation on whole exome sequencing in the diagnosis of rare diseases. Currently a PhD student at the school of biomedical sciences and oncology at the University of Turin Her interests are:

  • RNA biology
  • KRAS biology
  • Long-read sequencing

Federica Schieppati

Master student


Alumni


Mara Maldotti

Ph.D.

Mara managed the experimental studies of our research projects, contributing to the develoment and test of ASOs to challange new RNA targets. She is now part of grant office at the University of Milan.


Francesca Priante

Ph.D.

Francesca contributed to the development of a novel version of RNAmotifs aiming at associate multivalent RNA motifs with cognate trans-acting factors under a condition of interest. During her PhD she partecipated at the identification of novel actionable RNA defeacts in bone sarcomas enrolled within he Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas (NCT04621201) Trial.


Sarah Perrone

Ph.D.

Sarah contributed to the development of a version of GSECA aiming at detecting altered gene sets from single cell RNA sequencing data. During her PhD she analyzed the adaptation of medulloblastoma transcriptomes upon chemiotherapy. She now is into industry!


Shruti Sinha

Ph.D.

Sinha analyzed direct mRNA Nanopore sequencing data in prostate cancer. She is now Bioinformatics Scientist at Al Jalila Children's Speciality Hospital (AJCH) in Dubai!


Livia Caizzi

Ph.D.

Livia contributed to the experimental validations of FOXA1-mediated regulation of alternative splicing in prostate cancer. During the mounths spent in our lab she was also responsible for the devolopment of several other projects aiming at understanding alternative splicing regulation in cancer. She is now post-doc in the Epigenetics Lab of Prof Oliviero at the University of Turin!


Marco Del Giudice

Ph.D.

Marco contributed to the identified of pioneer transcription factor FOXA1 as the key controller of alternative splicing in prostate cancer. His contribution revealed that FOXA1 controls selection of splice variants that predict disease relapse and might be new drug targets to improve patient survival. He is now data scientist at industry!


Alberto Rissone

Research Fellow

Alberto importantly contributed to the improvment of RNAmotifs, which can now associate multivalent RNA motifs with cognate RNA binding proteins. He is data scientist at industry!


Lucilla Bracco

Internship student

Lucilla analyzed DNA somatic alterations in pediatric Ewing's sarcoma.


Fabiola Varese

Research Fellow

Fabiola extensively worked on long-read Oxford Nanopore Technologies and traditional short-read Illumina sequencing approaches. She now moved to pharma!


Jessica Giordano

Ph.D.

Jessica was involved in trascriptomic analyses of breast cancer chemioresistant tumors. She is now professor at secondary high school and still free-lance bioinformatician collaborating with us!


Greta Romano

Ph.D.

Greta worked on the characteziation of tumor evolution within the Genomic Profiles Analysis in Children, Adolescents and Young Adult With Sarcomas (NCT04621201) Trial, focusing on DNA somatic alterations. She decided to foster her training in Biology and she is now enrolled in postgraduate school of Medicine at the University of Parma.


Federica Gaudino

Ph.D.

Federica was the first biologist post-doc in our lab. She contributed to settle our experimental biology lab, implementing the Oxford Nanopore Technologies direct mRNA protocol and the Lexogen CORALL protocol for total mRNA sequencing. She is now professor at secondary high school!


C.G.B. friends  

We discuss our ideas with talented people:

Chiara Ambrogio

Armenise/Harvard Laboratory of Molecular Oncology
Turin, IT

Uberto Pozzoli

Bioinformatics lab
Bosisio Parini, IT

Michele Caselle
Matteo Osella

Department of Theoretical Physics
Turin, IT

Prabhakar Rajan

UroSplice lab
London, UK

Salvatore Oliviero

Dept. of Life Sciences & Systems Biology
Epigenetics Lab
Turin, IT

Davide Cacchiarelli

Armenise/Harvard Laboratory of Integrative Genomics
Naples, IT

Franca Fagioli

Paediatric Onco-Haematology, Stem Cell Transplantation and Cellular Therapy Division, City of Science and Health of Turin, Regina Margherita Children’s Hospital
Turin, IT

Francesca Ciccarelli

Cancer Systems Biology lab
London, UK

Jernej Ule

RNA Regulatory Networks lab
London, UK